Peptides / NAC (N-Acetyl Cysteine)
NAC (N-Acetyl Cysteine)
(NAC, N-Acetyl Cysteine, Acetylcysteine)T1supplementclinical
Biomarker Effects
CRP
↓ moderate
Anti-inflammatory signaling
IL-6
↓ small
Cytokine modulation
TNF-alpha
↓ small
Cytokine modulation
Oxidative stress
↓ moderate
Antioxidant effects
NAD+ levels
↑ moderate
NAD+ precursor support
ATP production
↑ small
Supports mitochondrial function
Mitochondrial biogenesis
↑ small
PGC-1α signaling
Glutathione
↑ moderate
Cysteine donor for GSH
ALT
↓ small
Supports liver detoxification
AST
↓ small
Supports liver detoxification
Mucus viscosity
↓ small
Mucolytic effects
Insulin sensitivity
↑ small
Reduces oxidative stress
Homocysteine
↓ small
Improves redox balance
GSH/GSSG ratio
↑ small
Improves redox balance
Dosing & Pharmacokinetics
Typical Dose600 mg
Frequencydaily
Routeclinician-directed
Half-Life2.3 hr
Safety & Evidence
NAC is a precursor to glutathione, used as a mucolytic and hepatoprotective agent. FDA-approved for acetaminophen overdose and respiratory conditions.
Sources
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