ATP production
Increase · moderate
Stabilizes mitochondrial cardiolipin
Literature evidence
Compound library
Vivy evidence dossier
SS-31 (Elamipretide)
Also indexed as Elamipretide, SS-31, MTP-131
T2Peptides
Read this entry as context, not instruction.
Evidence labels describe the material available in this reference entry. They do not establish that a compound is appropriate, effective, or safe for you. Inclusion is not a recommendation to use it.
Reference context
Pharmacokinetic context
Half-life2 hr
This field summarizes the library record. Half-life can vary with formulation, indication, and individual clinical context.
Observed relationships
Biomarker context
Mitochondrial membrane potential
Increase · moderate
Improves electron transport efficiency
Literature evidence
Oxidative stress
Decrease · moderate
Reduces mitochondrial ROS
Literature evidence
Mitochondrial biogenesis
Increase · small
Supports mitochondrial turnover
Literature evidence
Cardiolipin oxidation
Decrease · moderate
Protects inner mitochondrial membrane
Literature evidence
Fatigue
Decrease · small
Improves cellular energy availability
Literature evidence
Exercise tolerance
Increase · small
Enhanced mitochondrial function
Literature evidence
Lactate
Decrease · small
Improves oxidative metabolism
Literature evidence
Cardiac output
Increase · small
Improves mitochondrial efficiency in myocardium
Literature evidence
Endothelial function
Increase · small
Reduces mitochondrial ROS
Literature evidence
Mitochondrial function
Increase · moderate
Protects respiratory chain
Literature evidence
ROS
Decrease · moderate
Reduces mitochondrial ROS
Literature evidence
Fatty acid oxidation
Increase · small
Improves mitochondrial metabolism
Literature evidence
Exercise recovery
Increase · small
Improves mitochondrial repair
Literature evidence
Mitochondrial DNA damage
Decrease · small
Protects mitochondrial DNA
Literature evidence
Keep in view
Safety discussion points
SS-31 (elamipretide) is a mitochondria-targeted peptide that improves mitochondrial function. In clinical trials for mitochondrial diseases. Not FDA-approved.
Keep the reference close
Track SS-31 (Elamipretide) in context.
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