Peptides / Tesamorelin
Tesamorelin
(Egrifta, Tesamorelin)T1peptideclinical
Biomarker Effects
IGF-1
↑ moderate
GHRH analog
Waist circumference
↓ small
Reduces visceral fat
Growth hormone
↑ large
Stimulates pituitary GH release
IGFBP-3
↑ moderate
GH-mediated binding proteins
Fasting glucose
↓ moderate
Improves insulin sensitivity
HbA1c
↓ small
Improves glycemic control
Fasting insulin
↓ moderate
Reduces insulin resistance
HOMA-IR
↓ moderate
Improves insulin sensitivity
Triglycerides
↓ small
Improves lipid metabolism
HDL cholesterol
↑ small
Improves lipid profile
Dosing & Pharmacokinetics
Typical Dose1 mg
Frequencydaily
Routeclinician-directed
Half-Life4 hr
Safety & Evidence
Tesamorelin is a synthetic GHRH analog approved by FDA for HIV-associated lipodystrophy. Promotes GH and IGF-1 secretion.
Sources
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